Harrison’s Principles of Internal Medicine

For over 70 years, Harrison’s Principles of Internal Medicine has been the world’s most trusted and comprehensive reference for the science and practice of clinical medicine. The 22nd Edition continues this legacy, offering updated guidelines, practice-changing evidence summaries, and a fully revised structure to meet the needs of modern healthcare professionals.

Authored by leading experts including Dan Longo, Anthony S. Fauci, and Dennis L. Kasper, this two-volume edition provides deep insights into disease mechanisms, diagnostic reasoning, and therapeutic strategies. It features over 3,000 high-quality clinical, pathological, and radiographic images, detailed algorithms, and expertly crafted decision trees to guide accurate diagnosis and patient management.

New chapters explore emerging topics such as COVID-19 and other coronavirus infections, physician well-being, principles of immunization, and point-of-care ultrasound. Whether for reference, research, or clinical application, Harrison’s remains the definitive resource for students, physicians, and medical professionals who demand excellence in patient care.